Genetic diseases or abnormalities are problems, dysfunctions and diseases related to oral tissues and dentition caused by defective genes. The enamel is one of the four major tissues that make up a tooth. It’s the hardest substance on the human body containing the highest amount of minerals.
Tooth disorders and solution to teeth grinding are just one of the best discussion that this site could offer
It’s formed on the tooth when the tooth develops within the gum before erupting into the mouth. Since it’s the outermost layer, it is open to dental problems including genetic tooth enamel disorders.
Few disorders are discussed below
DentinogenesisImperfecta is an inherited tooth disorder where the chip of the enamel layer comes off resulting in a weak tooth that is inclined to damage and sensitivity.
Discolouration is one of the characteristics of this disorder, where the teeth turn either bluish grey or yellowish brown colours. Primary teeth and the secondary are both affected by this disorder. There are 3 types of Dentinogenesis Imperfecta namely; Type 1: This is inherited in Autosomal Recessive manner, Type 2 and Type 3: This is inherited in Autosomal Dominant manner that is the mutation of the DSPP gene occurs.
The main aim of treatment is to protect the teeth.
This disorder is not as frequent as many other genetic tooth enamel disorders out there. Less than a thousand people are subjected to this type of genetic teeth disorder annually but be that as it may, it still warrants some attention.
Since this disorder makes the enamel of the tooth weak, the tooth is prone to damage and urgent interventions are required.
48, XXYYY Syndrome
This is a rare condition that affects about 18,000 males. The disorder not only interferes with our sexual development but also causes common dental problems. Infertility as well as abnormal body growth and reduced height are some of its causes.
Amelogenesis imperfect (AI): This is a group of genetically-inherited disorders of teeth development that is characterized by thin enamel and abnormal enamel formation. There are four subdivisions
- Type 1- Hypoplastic
- Type 2 – Hypomaturatio
- Type 3 – Hypocalcified
- Type 4 – Hypomaturation/Hypoplasia/Taurondontism
Main symptoms can be characterized by missing tooth enamel or defective enamel. Cracked tooth as well as early tooth decay and or loss are some other symptoms you may experience. Teeth are sensitive either to hot or cold matters or sometimes both.
Mutations in particular genes have been recognized as the cause of at least 17 subtypes of Amelogenesis imperfecta.
Family dental history plays a major role in genetic teeth disorders. And should the above symptoms be noticed, immediately dental consultation should be sought.